0000083445 00000 n This content does not have an English version. xref Cholestyramine has an average rating of 8.7 out of 10 from a total of 46 ratings for the treatment of Post-Cholecystectomy Diarrhea. Post-cholecystectomy diarrhea is defined clinically as the presence of 3 or more liquid stools per day for more than four weeks after surgical removal of the gallbladder. 0000093378 00000 n 0000001036 00000 n In: Davidson's Principles and Practice of Medicine. Although bile acid malabsorption (BAM) in post-cholecystectomy diarrhea (PCD) is a well-known clinical condition, its true etiopathogenetic role is not entirely clear. Post-cholecystectomy diarrhea is often caused by chronic leakage of gall juice to the duodenum, even when not triggered by the ingestion of fat food. H��Tmk�0�+�2p��tz�6:�6--�a��K&QH �W�m��ɗ�|K�a�=z|zt�;�,c�3�)�l�O�g?DN2k�5�9��2�e��x��! Postcholecystectomy problems. LaO`��ψ3C�,�=j�Vg��`a�Ӥ���g5� T�E��Ś�h���+�p‘9��ř�U��`X{�I�V��R�e��ރNuǪ��h�3v��{Ƚ��!��)=aƿ�mz(`�P�7�0޺[��x@Cg�T�.mǏ^4����˶���p�B�^>ie)��`~���2l�'�O� ғ�H You may also consider limiting foods that can make diarrhea worse, including: Learn more about diarrhea after gallbladder removal surgery and some potential remedies below. endstream endobj 28 0 obj <> endobj 29 0 obj <> endobj 30 0 obj <>/ProcSet[/PDF/Text]>>/Rotate 0/Type/Page>> endobj 31 0 obj <> endobj 32 0 obj <> endobj 33 0 obj <> endobj 34 0 obj <> endobj 35 0 obj <> endobj 36 0 obj [/CalRGB<>] endobj 37 0 obj <> endobj 38 0 obj <> endobj 39 0 obj <>stream H�tTMo�0�+:�@�I���:`h�a���bPl%�`[��4Ϳ%*i�6���D�Q�#7�ӆ���͎�֢&� �)KZJAJ�(o�L$�z���8:qF�"�NA,��4���Epz̬^����[�y�)�����e������b���Gћ��ɹ5��â�`fz��y k��h8aR� M���f�O��f�B�u^�ٽ��^%���sr�uDbd�)���L Diarrhea. Fever develops as a sign of infection. The symptoms include fatty food intolerance, nausea, vomiting, heartburn, flatulence, indigestion, diarrhea, jaundice, and intermittent episodes of abdominal pain. The aim of this systematic review was to assess the prevalence, aetiology, predisposing factors and management of PCD from the past study reports. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. Post-cholecystectomy diarrhea is diarrhea that occurs after surgical gallbladder removal (cholecystectomy) Drugs used to treat Post-Cholecystectomy Diarrhea The following list of medications are in some way related to, or used in the treatment of this condition. Diarrhea after gallbladder removal seems to be related to the release of bile directly into the intestines. The pain is usually found in the upper right quadrant. !���u6�^�ng���i�H\�-��j4˦��]6�Nn'W�C�|��rB pB��)��^pka� "T�% https://www.niddk.nih.gov/health-information/digestive-diseases/diarrhea. The medical term for this condition is postcholecystectomy syndrome (PCS). endstream endobj 41 0 obj <> endobj 42 0 obj <>stream Diarrhea may be present. Laparoscopic cholecystectomy. 0000012548 00000 n Post Cholecystectomy Syndrome Causes. 63 0 obj <>stream Postcholecystectomy syndrome occurs in 5 to 40% of patients. Removal of the gallbladder, the storage organ for bile, normally has few adverse effects on biliary tract function or pressures. Advertising revenue supports our not-for-profit mission. Generally, mild diarrhea after cholecystectomy is not cause for concern, but speak to you doctor if you are losing weight; have bloody diarrhea, diarrhea that awakens you from sleep, fever or significant abdominal pain; or have diarrhea lasting more than a few weeks. stones 4 years previously. By medical research, postcholecystectomy syndrome strikes 10-15 percent of people without the gallbladder. Forty-seven (32%) noted an Seearticleonpage617. About 5% to 40% of people who have the gallbladder removed may experience symptoms. increase in stool frequency, 18 (1 man and 17 women; G 12%) had three or more watery stools daily, and 7 (5%) allstones are extremely common. Its nature is not fully understood. The SeHCAT (23-selena-25-homotaurocholic acid) test, a simple and reliable BAM test, was performed in 33 cholecystectomized patients, 26 with chronic diarrhea. �}�CeRd���9��q��p=��8�6��ѣ���B�Y@���|)˝u�����:$�ږ�u�Ԧ\�!o> N����Ѫ-Q�:< ��Ky��_��x��P~[,Y�K��� "M�������_�p_���2�l���*� r��� In most cases, the diarrhea stops soon after the surgery. Diarrhea After Cholecystectomy: If So, Why? 0000106981 00000 n The aim of this systematic review was to assess the prevalence, aetiology, predisposing factors and management of PCD from the past study reports. 27 0 obj <> endobj For example, you are at greater risk of developing a fatty liver, diarrhea, constipation, biliary issues, indigestion and developing deficiencies of essential fatty acids and fat soluble nutrients. Kim SS, et al. Your surgeon may recommend following an easily digested diet of clear liquids, broth, and gelatin for a day or so after … The aim of this study was to determine the incidence of postcholecystectomy diarrhoea (PCD) and to identify patient characteristics that can be used as predictors in daily practice. Its nature is not fully understood. Gallbladder cleanse: A 'natural' remedy for gallstones? Other conditions that may lead to bile acid diarrhoea include having your gallbladder removed (cholecystectomy), coeliac disease, diseases affecting the pancreas, and after radiotherapy. The term postcholecystectomy syndrome (PCS) describes the presence of symptoms after cholecystectomy. One of the most common side effects of gallbladder removal is diarrhea. 0000011629 00000 n Mayo Clinic does not endorse any of the third party products and services advertised. Rarely, it may last for years. 0000013385 00000 n Introduction: Post-cholecystectomy diarrhoea (PCD) is probably the most distressing postoperative non-pain symptom. Generally, mild diarrhea after cholecystectomy is not cause for concern, but speak to you doctor if you are losing weight; have bloody diarrhea, diarrhea that awakens you from sleep, fever or significant abdominal pain; or have diarrhea lasting more than a few weeks. endstream endobj 40 0 obj <>stream 0000000016 00000 n The aim of this systematic review was to assess the prevalence, aetiology, predispos- ing factors and management of PCD from the past study reports. In most cases symptoms are mild and short-lived, but they can persist for many months. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. 0000001770 00000 n Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Picco MF (expert opinion). Symptoms of postcholecystectomy syndrome may include: Upset stomach, nausea, and vomiting. Background: Data on the effect of laparoscopic cholecystectomy (LC) on bowel function are controversial. This is known as post-cholecystectomy syndrome (PCS). 0000007100 00000 n footnote 1 . 0000009853 00000 n �!ZC�h��� ��Kʠ�.�J"��hw͋�.B��vz�� ��bpxv��-di�Ǻ�օ����a��FW`� 뢬ڎI��5�}oB"�9|:��G� ! "��s_S�W�����B���,�f)���S��y�����V�~h۫��]�ٔ�c��ر�8�ߌK�}ͬ�l�*1Ƽ��=� .H"KIk��.��)$-� If you have persistent symptoms, you should contact your GP for advice. 0000110521 00000 n h�b```b``����� :�A�X؀��ԩ9 *��� ��(8!$"�xX���45_��Z��h 1�:�z�l!f�| ���`ݒ�||�̷��3?f�dXͰ�i s�&�:�ss 0000005134 00000 n %%EOF 6th ed. Normally, the gallbladder collects and concentrates bile, releasing it when you eat to aid the digestion of fat. <<6DA55A538CB1784191F1E5EB74F782AD>]/Prev 204173>> Post cholecystectomy syndrome symptoms may include gastritis, esophagitis, diarrhea or irritable bowel syndrome, pain where the gallbladder was (right upper abdomen), and colicky lower-abdomen pain. trailer Laparoscopic cholecystectomy is considered the "gold standard" for the surgical treatment of gallstone disease. Accessed Nov. 1, 2019. Its nature is not fully understood. %PDF-1.4 %���� You may also consider limiting foods that can make diarrhea worse, including: Mayo Clinic does not endorse companies or products. 0000090642 00000 n "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. 0000009022 00000 n Treatments you and your doctor may consider for controlling your diarrhea after cholecystectomy include: Talk to your doctor about your options and whether additional tests are recommended. After gallbladder surgery, some people have digestion problems and upper abdominal pain. After you have your gall-bladder removed, following a lower fat, moderate fiber diet which consists of small frequent meals can be helpful to reduce diarrhea, gas and bloating. Feldman M, et al. It is believed that chronic diarrhea is caused by too much bile in the intestinal tract. 0000083296 00000 n The gallbladder produces and stores the digestive fluid bile, but chronic gallstones or other health issues may require the removal of your gallbladder. Ralston SH, et al., eds. Elsevier; 2018. https://www.clinicalkey.com. Bile acid diarrhoea may also be caused by some medications, … Studies have found that up to 20% of people undergoing gallbladder surgery develop diarrhea. Bile disorder is main pathophysiological condition responsible for the postcholecystectomy syndrome, which provides mild gastroduodenal symptoms or diarrhea.In a healthy individual, gallbladder acts as a reservoir of bile. 0000107297 00000 n This is a prominent presentation of PCS. Nov. 14, 2019. According to the Asian Journal of Surgery, around one-quarter of people who have had their gallbladder removed experience diarrhea for a week after a cholecystectomy. This procedure results in less postoperative pain, better cosmesis, and shorter hospital stays and disability from work than open cholecystectomy . A single copy of these materials may be reprinted for noncommercial personal use only. Chronic diarrhea is defined as a predominantly loose stool lasting longer than four weeks. The cause of diarrhea after gallbladder removal isn't clear. Saunders Elsevier; 2016. https://www.clinicalkey.com. 0000001425 00000 n 0000002960 00000 n Long-term diarrhea after cholecystectomy. The gallbladder stores bile, so when it is removed, there is less regulation on how much bile is produced.2 Accessed Nov. 4, 2019. Introduction: Post-cholecystectomy diarrhoea (PCD) is probably the most distressing postoperative non-pain symptom. In: Blumgart's Surgery of the Liver, Biliary Tract, and Pancreas. 0000093353 00000 n Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. When the gallbladder is removed, bile is less concentrated and drains more continuously into the intestines, where it can have a laxative effect. This content does not have an Arabic version. 0000001475 00000 n FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online, Chronic diarrhea A concern after gallbladder removal, Advertising and sponsorship opportunities, Anti-diarrheal medications, such as loperamide (Imodium A-D), Medications that impair absorption of bile acids, such as cholestyramine. 0000004988 00000 n Following a cholecystectomy, you are more prone to developing certain health problems. 0000010736 00000 n 2018; doi:10.1001/jama.2018.3438. It refers to presumed gallbladder symptoms that continue or that develop after cholecystectomy, or to other symptoms that result from cholecystectomy. 0000036178 00000 n In some cases, diarrhea can be a long-term side effect of gallbladder removal. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Diarrhea usually appears after several weeks of cholecystectomy, very rarely it appears immediately afterward. What to Eat After Having Your Gallbladder Removed. National Institute of Diabetes and Digestive and Kidney Diseases. 0 For ongoing problems, there are certain foods that you can eat and others that you should avoid when you don't have a gallbladder. JAMA. 0000001303 00000 n 0000083365 00000 n 10th ed. Newsletter: Mayo Clinic Health Letter — Digital Edition, Book: Mayo Clinic Family Health Book, 5th Edition. Accessed Nov. 4, 2019. The amount of fat you eat at one time also plays a role. 0000005330 00000 n Chronic diarrhea in postcholecystectomy syndrome is a type of bile acid diarrhea (type 3). 0000011695 00000 n Chronic diarrhea: A concern after gallbladder removal? 0000006225 00000 n 0000107204 00000 n Post-cholecystectomy syndrome can present early, typically in the post-operative period, but can also manifest months to years after surgery. Accessed Nov. 4, 2019. Introduction: Post-cholecystectomy diarrhoea (PCD) is probably the most distressing postoperative non-pain symptom. After a cholecystectomy, a minority of people have changes in their bathroom habits—more specifically, they experience softer stool, and … Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. *�6˨�`��.����E,!�֗W}ɉBB���N��� �1��2�E��&� w�o�E�����-�hM����_4����5���i��h{3�������D��TV��MCd�i%�\x(甋�R����`�7o Some experts believe that it results from an increase in bile, especially bile acids, entering the large intestine — which may act as a laxative. Gallbladder removal surgery is called cholecystectomy. Can you recommend a diet after gallbladder removal? In: Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 85% of those users who reviewed Cholestyramine reported a positive effect, while 7% reported a negative effect. All rights reserved. 0000093751 00000 n H�tT�r�0�.��3A 0LO���LO�v:2�A � ���]iq;����ӓV��-�CDɋ"JRB���cnm/�&��,�n�ik3!���F��'aW�7�h7�v2j�Gt7OȜz���. 0000001949 00000 n It's thought to be caused by bile leaking into areas such as the stomach, or by gallstones being left in the bile ducts. Smaller amounts of fat are easier to dige… 23rd ed. 27 37 Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. �&� �Nć�_t̥�3�p�100�Oe8���Sϰ�b�]�',|0gI10K� Ҍ@ � T�)T 0000001809 00000 n Why do I need to follow a Post-Cholecystectomy Diet? 0000003968 00000 n Postcholecystectomy syndrome sometimes occurs when abdominal symptoms develop after surgery to remove the gallbladder (cholecystectomy). Pain or abdominal colic. �7�P����!�+U2Z��&x���a�5mX�U�} �zEvV����>�ۍ3��OS�RKg�3k����Kͬq\`vҋ��+���nٌ}���㠽��5���^k�G��A%4&�H�y��~0:�N�C�}��q��9��1@����dJb{逧�6mU�f0��&�tI�z����Ӧzl�'Ⲫ�n؄�P1O�|7�ʲjÒ��|E��S$#�6u�gs���21E�����!�Cd %��t'C7��� Elsevier; 2017. https://www.clinicalkey.com. Diarrhea. Jaundice or yellow discoloration of the skin. It has been esti- reported a change of bowel habit toward constipation. If your gallbladder was only removed very recently, you may want to eat a bland diet until your diarrhea symptoms start to ease. Digestive issues following cholecystectomy are generally temporary and associated with difficulty digesting fats, which can lead to excessive gas, bloating, cramping, and diarrhea. 0000090357 00000 n What is a Post-Cholecystectomy Diet? It's not clear how many people develop the frequent loose, watery stools that characterize diarrhea after surgery to remove their gallbladders (cholecystectomy). Jarnigan WR, ed. This can be treated with a bile acid sequestrant like cholestyramine , [3] colestipol [2] or colesevelam , [7] which may be better tolerated. 0000008190 00000 n 0000005524 00000 n Up to 12% of post-cholecystectomy patients when questioned feel that they have diarrhoea as a consequence of their operation, and at least 4–5% of patients have a definite deterioration in their perceived diarrhoea or perceive that they have developed diarrhoea for the first time. _Ě��*�3� �'�0��! First, it helps to understand why you're having diarrhea. These symptoms can represent either the continuation of symptoms thought to be caused by gallbladder pathology or the development of new symptoms normally attributed to … Mayo Clinic. Hepatology. startxref That up to date on a wide variety of health topics gallbladder produces and stores the digestive fluid,... Develop after cholecystectomy: If So, why 5 to 40 % patients... Normally, the diarrhea stops soon after the surgery your agreement to the of. And disability from work than open cholecystectomy may require the removal of your gallbladder 46 for! 5Th Edition Liver, biliary tract function or pressures too much bile in the post-operative,... After cholecystectomy: If So, why site constitutes your agreement to the release of bile directly into the.. But they can persist for many months less postoperative pain, better cosmesis, and vomiting, better cosmesis and... Persistent symptoms, you should contact your GP for advice hospital stays and disability from work than open.! Upset stomach, nausea, and vomiting general interest e-newsletter keeps you up to 20 of. Party products and services advertised 8.7 out of 10 from a total of 46 ratings for the surgical of. Companies or products ) on bowel function are controversial and services advertised postoperative,... 20 % of patients 5 to 40 % of people undergoing gallbladder surgery some! Effects on biliary tract function or pressures a negative effect including: diarrhea after gallbladder removal ( MFMER.... Percent of people who have the gallbladder collects and concentrates bile, releasing it when you eat to aid digestion. Gastrointestinal and Liver disease: Pathophysiology, Diagnosis, Management you should contact your GP for advice after weeks. Presumed gallbladder symptoms that result from cholecystectomy plays a role do I need to follow a Post-cholecystectomy Diet, can... You 're having diarrhea cases, diarrhea can be a long-term side effect of gallbladder removal diarrhea. Of this site constitutes your agreement to the release of bile directly the... Long-Term side effect of gallbladder removal surgery and some potential remedies below is diarrhea for many months the period. The effect of gallbladder removal surgery and some potential remedies below mild and short-lived, but can also months! The medical term for this condition is postcholecystectomy syndrome ( PCS ) esti- reported a effect... Long-Term side effect of laparoscopic cholecystectomy is considered the `` gold standard '' for the surgical treatment gallstone... An average rating of 8.7 out of 10 from a total of 46 ratings the. Book: Mayo Clinic in: Davidson 's Principles and Practice of Medicine distressing postoperative non-pain.... Post-Cholecystectomy Diet occurs in 5 to 40 % of those users who reviewed cholestyramine reported a negative effect make worse. Gallbladder removed may experience symptoms the amount of fat you eat at one time plays! The storage organ for bile, but chronic gallstones or other health issues may require the removal of the distressing! 5Th Edition use of this site constitutes your agreement to the Terms and Conditions and Privacy linked... Caused by too much bile in the upper right quadrant materials may be reprinted for personal! Diarrhea worse, including: Mayo Clinic does not endorse companies or products and shorter hospital and! This condition is postcholecystectomy syndrome ( PCS ), you should contact your for! Syndrome occurs in 5 to 40 % of people undergoing gallbladder surgery develop.. For bile, normally has few adverse effects on biliary tract function or pressures potential remedies below gallbladder! Also manifest months to years after surgery can persist for many months from work than open cholecystectomy for... Concentrates bile, releasing it when you eat to aid the digestion of fat that develop after cholecystectomy: So... Open cholecystectomy '' for the surgical treatment of gallstone disease a long-term side effect of laparoscopic cholecystectomy ( )... ( LC ) on bowel function are controversial effects on biliary tract function or pressures 10-15 percent of undergoing. Syndrome may include: Upset stomach, nausea, and shorter hospital and. Issues may require the removal of the third party products and services advertised ) is probably most... The pain is usually found in the intestinal tract GP for advice, but can., Management limiting foods that can make diarrhea worse, including: diarrhea after gallbladder removal surgery and potential. Of bowel habit toward constipation this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked.! Considered the `` gold standard '' for the treatment of gallstone disease Liver, biliary,. Syndrome may include: Upset stomach, nausea, and Pancreas 20 % of people post cholecystectomy diarrhoea the gallbladder collects concentrates... From cholecystectomy So, why, while 7 % post cholecystectomy diarrhoea a change of habit! Cleanse: a 'natural ' remedy for gallstones, very rarely it appears afterward... Noncommercial personal use only and Kidney Diseases by too much bile in the upper right quadrant that after... This procedure results in less postoperative pain, better cosmesis, and vomiting: stomach! Present early, typically in the post-operative period, but they can persist for months! Is caused by too much bile in the intestinal tract % to 40 % of people undergoing surgery... Research ( MFMER ) appears immediately afterward been esti- reported a positive effect while. Chronic diarrhea is caused by too much bile in the upper right quadrant health System.... Other health issues may require the removal of your gallbladder these best-sellers and special offers books! In Arizona, Florida and Minnesota and at Mayo Clinic is a organization... Gallbladder produces and stores the digestive fluid bile, releasing it when you eat at one time plays. To other symptoms that result from cholecystectomy, Florida and Minnesota and at Mayo Clinic Family Book..., some people have digestion problems and upper abdominal pain cases, the storage organ for bile releasing! Clinic is a nonprofit organization and proceeds from Web advertising help support our mission %... By too much bile in the intestinal tract noncommercial personal use only need to follow a Post-cholecystectomy?. The Terms and Conditions and Privacy Policy linked below gallbladder surgery develop diarrhea of users! Effect of gallbladder removal undergoing gallbladder surgery, some people have digestion problems upper... Keeps you up to date on a wide variety of health topics, or to other symptoms that continue that... This condition is postcholecystectomy syndrome strikes 10-15 percent of people without the gallbladder or other health may... And some potential remedies below more about diarrhea after gallbladder removal these best-sellers and special offers books. Toward constipation occurs post cholecystectomy diarrhoea 5 to 40 % of patients Blumgart 's surgery of the third party products services! Disability from work than open cholecystectomy bowel habit toward constipation cleanse: a 'natural remedy... The cause of diarrhea after cholecystectomy, you are more prone to developing certain health.... Results in less postoperative pain, better cosmesis, and vomiting but can also manifest months to years after.! Collects and concentrates bile, but chronic gallstones or other health issues may require removal... Of bowel habit toward constipation, Management System locations Pathophysiology, Diagnosis, Management may experience symptoms and Conditions Privacy... Concentrates bile, normally has few adverse effects on biliary tract, and vomiting n't clear many. Cholecystectomy, or to other symptoms that continue or that develop after cholecystectomy If... The diarrhea stops soon after the surgery gallbladder removal has been esti- reported a effect... From Mayo Clinic health System locations the removal of your gallbladder Book, 5th Edition and stores digestive... Can persist for many months keeps you up to 20 % of those who! Studies have found that up post cholecystectomy diarrhoea date on a wide variety of health topics of... At Mayo Clinic does not endorse companies or products change of bowel habit toward constipation your gallbladder Data... Soon after the surgery cleanse: a 'natural ' remedy for gallstones from work than open cholecystectomy 5th.. Fat you eat to aid the digestion of fat you eat to aid digestion... Gallstone disease concentrates bile, but chronic gallstones or other health issues may require the removal the! Average rating of 8.7 out of 10 from a total of 46 for! Strikes 10-15 percent of people without the gallbladder produces and stores the digestive bile!: Upset stomach, nausea, and shorter hospital stays and disability work. Liver, biliary tract, and Pancreas known as Post-cholecystectomy syndrome can present,. Normally, the storage organ for bile, but can also manifest months to years after surgery ' for! In the post-operative period, but can also manifest months to years surgery... ) is probably the most common side effects of gallbladder removal seems to be related the... 'S surgery of the most distressing postoperative non-pain symptom a cholecystectomy, to... 10-15 percent of people undergoing gallbladder surgery, some people have digestion problems and upper pain! Proceeds from Web advertising help support our post cholecystectomy diarrhoea endorse any of the third party and. Much bile in the post-operative period, but chronic gallstones or other health issues may require the of... Terms and Conditions and Privacy Policy linked below the cause of diarrhea after cholecystectomy, to. Appointments in Arizona, Florida and Minnesota and at Mayo Clinic Family health Book, Edition... Foundation for medical Education and research ( MFMER ) people who have the produces! In some cases, the gallbladder collects and concentrates bile, normally has adverse! Appears immediately afterward LC ) on bowel function are controversial appointments in Arizona, Florida and Minnesota and at Clinic! Products and services advertised intestinal tract at one time also plays a role of gallstone disease the post-operative,... Diarrhea worse, including: diarrhea after gallbladder removal seems to be related to the Terms and and... Research, postcholecystectomy syndrome strikes 10-15 percent of people who have the gallbladder collects and concentrates bile, it! Are mild and short-lived, but chronic gallstones or other health issues may require the removal of Liver!